Researchers study solution to combat bacterium that affects fish

  • The death of fish caused by pathogenic agents is a major problem for the national aquaculture industry. For this reason, researchers at the Faculty of Chemistry and Biology are developing a project to generate a new immunization strategy.


 

The death of fish caused by pathogenic agents is a major problem for the national aquaculture industry. For this reason, researchers at the Aquaculture Biotechnology Center of the Faculty of Chemistry and Biology are developing a Fondecyt Initiation Project to generate a new immunization strategy.

According to the Undersecretary of Fishing and Aquaculture, in 2013 the fishing production was 2.9 million tonnes, 1.2 million of which were allocated for exports. Thus, our country stands out for its aquaculture industry, being one of the largest salmon producers worldwide, right after Noruega.

However, one of the major problems faced by this industry is the number of diseases caused by pathogens like Piscirickettsia salmonis, a bacterium that causes tissue damage and loss of appetite in fish, leading to fish death, decreased production, reduced quality of the product and the subsequent social impact.

According to Dr Sebastián Reyes, professor at the Faculty of Chemistry and Biology, “We only need to remember the health emergency caused by ISA virus in salmon farming. It caused social damage, because all communities related to aquaculture ended like ghost towns.”

A project to contribute with salmon farming industry

Through the Fondecyt Project 11150807 “Passive immunization as a new control strategy against Piscirickettsia salmonis,” researchers seek to propose an innovative and effective alternative to combat this bacterium that only affects fishes in Chile. For this purpose, they are working on a passive immunization strategy that involves stimulating the immune system’s cells to prevent the Piscirickettsia salmonis from spreading.

“We suggest stimulating the fish by using a hyperimmune serum. The idea is to give this serum to primary cultures of infected cells from the immune system and see if the serum is able to activate them and degrade the bacteria inside. We also need to describe the infectious cycle of the bacterium studied to measure its impacts as they are unknown for now.”

The project is also supported by the ICTIO Biotechnologies Consortium, created through a CORFO (the Chilean Economic Development Agency) project, which is formed by the following entities: Activaq S.A., Australis Mar S.A., Productos del Mar Ventisqueros, Salmones Blumar and Universidad de Santiago de Chile.

The project seeks to find a concrete and viable solution for the salmon farming industry by directly involving researchers and related companies to contribute to this strategic productive sector of the country.

Translated by Marcela Contreras